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Hearing loss and auditory function in sickle cell disease
G Pamela Burch-Sims1, Valeria R Matlock
1Department of Speech Pathology and Audiology, College of Health Sciences, Tennessee State University, 330 Tenth Avenue North, Nashville, TN 37203, USA. Psims@tnstate.edu
Journal of Communication Disorders
|May 3, 2005
Summary
Sickle cell disease, a hereditary blood disorder, can impact hearing. Further research is needed to understand the link between sickle cell anemia and auditory function due to inconsistent findings.
Area of Science:
- Genetics and Hematology
- Otolaryngology
- Public Health
Background:
- Sickle cell disease (SCD) is an inherited hemoglobinopathy affecting red blood cells, leading to various complications.
- SCD affects 1 in 400 African-Americans in the US, with 1 in 10 having sickle cell trait.
- While neurological symptoms are common, the relationship between SCD and hearing loss is not well understood.
Purpose of the Study:
- To review the genetic and pathophysiological aspects of sickle cell disease.
- To evaluate the prevalence of hearing loss and auditory dysfunction in SCD patients.
- To compare hearing health risks in SCD patients versus the general population.
Main Methods:
- Literature review of studies on sickle cell disease and auditory health.
- Analysis of audiological assessment and treatment models for SCD patients.
- Examination of the pathogenesis of hearing impairment in the context of SCD.
Main Results:
- Inconsistent results exist regarding peripheral auditory sensitivity in SCD.
- The incidence of subjective hearing impairment in SCD is low, suggesting a focus on pathogenesis.
- Auditory damage is a potential concern due to the vaso-occlusive nature of SCD.
Conclusions:
- The relationship between sickle cell anemia and auditory function requires further investigation.
- A standardized audiological assessment model is needed for SCD patients.
- Understanding the link between SCD and hearing loss is crucial for comprehensive patient care.