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Ocular surface disorders and tear function changes in nodulo-cystic acne
Murat Ozdemir1, Gokhan Ozdemir, Sezai Sasmaz
1Kahramanmaras Sutcu Imam University, Medical Faculty, Ophthalmology Department, Kahramanmaras, Turkey.
The Journal of Dermatology
|May 3, 2005
Summary
Patients with nodulo-cystic acne frequently experience ocular surface disorders and altered tear function. These findings suggest that individuals with severe acne should undergo ophthalmological evaluation.
Area of Science:
- Ophthalmology
- Dermatology
- Ocular Surface Disease
Background:
- Nodulo-cystic acne is a severe form of acne vulgaris.
- Ocular surface and tear function alterations may be associated with acne treatments or the condition itself.
Purpose of the Study:
- To investigate ocular surface disorders and tear function changes in patients with nodulo-cystic acne.
- To compare findings between acne patients and healthy controls.
Main Methods:
- Ocular examinations were performed on 87 nodulo-cystic acne patients and 50 healthy controls.
- Tear film break-up time (BUT), Schirmer test, and corneal staining were assessed.
- Subjective ocular complaints were recorded.
Main Results:
- Abnormal tear film BUT and Schirmer scores were significantly more prevalent in the acne group.
- Corneal punctate epithelial erosions were observed in a small percentage of acne patients.
- Ocular complaints were significantly higher in acne patients compared to controls.
Conclusions:
- Tear function tests are significantly altered in patients with nodulo-cystic acne.
- Severe acne patients may benefit from referral to an ophthalmologist for comprehensive eye evaluation.