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Case report: A rare case of Ewing's sarcoma and osteosarcoma at different sites 10 years apart

Harish S Hosalkar1, Alfred Atanda, Julieta Barroeta

  • 1Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, USA.

Clinical Orthopaedics and Related Research
|May 3, 2005
PubMed

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...