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Perinatal outcome in multiple pregnancies--spontaneous gestation versus
M Gojnic1, K Jeremic, V Boskovic
1Medical Faculty of Belgrade, Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia and Montenegro.
Summary
Twin pregnancies from in vitro fertilization (IVF) do not show increased risk for negative perinatal outcomes compared to spontaneous twin pregnancies. This study compared IVF twins to matched spontaneous twins, finding similar outcomes.
Area of Science:
- Reproductive Medicine
- Perinatology
- Obstetrics
Background:
- In vitro fertilization (IVF) is a common method for assisted reproduction.
- Twin pregnancies are associated with higher risks of adverse perinatal outcomes compared to singleton pregnancies.
- The specific risks of twin pregnancies conceived via IVF versus spontaneous conception require further investigation.
Purpose of the Study:
- To compare the perinatal outcomes of twin pregnancies conceived through IVF with those of spontaneously conceived twin pregnancies.
- To determine if IVF-induced twin gestations face a greater risk of negative perinatal events.
Main Methods:
- A case-control study involving 240 patients with twin pregnancies.
- 120 patients with IVF-induced twin pregnancies were matched with 120 patients with spontaneous twin pregnancies based on age, education, and parity.
- Clinical monitoring, laboratory analyses, and ultrasonography were used to follow pregnancies.
Main Results:
- The study aimed to identify differences in perinatal outcomes between the two groups.
- Detailed clinical, laboratory, and ultrasonographic data were collected for all participants.
Conclusions:
- The investigation sought to clarify the perinatal risks associated with IVF-assisted twin pregnancies.
- Findings are expected to inform clinical guidance and patient counseling regarding IVF and twin gestation.