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Updated: Aug 15, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
[Surgical treatment of ischemic heart disease using internal thoracic artery and partial ileal bypass]
Insights
This study recommends a two-stage treatment for ischemic heart disease, combining coronary artery bypass surgery with partial ileal bypass to manage lipid levels. This complex approach showed good clinical effects in patients.
Area of Science:
- Cardiovascular Surgery
- Metabolic Surgery
- Cardiology
Background:
- Ischemic heart disease (IHD) often involves complex pathophysiology, including coronary artery blockages and dyslipidemia.
- Current treatments may not adequately address both the structural and metabolic aspects of IHD.
- Partial ileal bypass is a surgical option for managing lipid disorders.
Purpose of the Study:
- To evaluate a complex two-stage treatment for ischemic heart disease.
- To assess the efficacy of combining coronary artery reconstruction with partial ileal bypass.
- To explore partial ileal bypass as a standalone treatment for dyslipidemia and diffuse coronary artery disease.
Main Methods:
- Operative treatment of 150 patients with IHD.
- Utilizing the internal thoracic artery for coronary artery bypass grafting.
- Performing partial ileal bypass to correct plasma lipid spectrum disturbances.
- Analyzing clinical outcomes of complex two-stage surgical interventions in 60 patients.
Main Results:
- The internal thoracic artery graft demonstrated advantages over autovein grafts in coronary artery reconstruction.
- Complex two-stage treatment in 60 patients resulted in a good clinical effect.
- Partial ileal bypass showed promise as an independent intervention.
Conclusions:
- A complex two-stage treatment involving coronary artery reconstruction and partial ileal bypass is recommended for ischemic heart disease.
- Internal thoracic artery grafts are favored for coronary artery bypass.
- Partial ileal bypass is a viable option for dyslipidemia and diffuse coronary artery disease.
Abstract:
The authors recommend complex two-stage treatment of ischemic heart disease, including a reconstructive operation on the coronary arteries and an operation for correcting the disturbed plasma lipid spectrum (partial ileal bypass). The results of operative treatment of 150 patients with the use of the internal thoracic artery were studied. The authors emphasize the advantages of this operation over one using an autovein graft. Complex operative treatment was conducted in the clinic in 60 patients with a good clinical effect. The authors also recommend operation for partial ileal bypass as an independent intervention in dyslipoproteinemia and diffuse affection of the coronary arteries.

