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Bioluminescence Imaging of NADPH Oxidase Activity in Different Animal Models
Published on: October 22, 2012
Imaging of photodynamically generated singlet oxygen luminescence in vivo
Mark J Niedre1, Michael S Patterson, Anoja Giles
1Department of Medical Biophysics, Ontario Cancer Institute and University of Toronto, Toronto, Ontario, Canada.
Photochemistry and Photobiology
|May 4, 2005
Abstract:
We describe a novel scanning-laser system for imaging type-II photodynamically generated singlet oxygen (1O2[1delta(g)]) luminescence and demonstrate it in vivo in an intradermal tumor model in mice. We verify the strong oxygen-dependence of the signal and show that the images are near the practical resolution limit.
