Related Experiment Video
Updated: Aug 18, 2026

Echocardiographic and Histological Examination of Cardiac Morphology in the Mouse
Published on: October 26, 2017
Hypertrophy in the female heart
Deborah L Crabbe1, Nieka K Harris
1Temple University School of Medicine, 3420 North Broad Street, Room 824 MRB, Philadelphia, PA 19140, USA. dcrabbe@temple.edu
Abstract:
Several clinical studies have suggested that sex influences the left ventricle's response to altered loading conditions and thus the development of cardiac hypertrophy. Likewise, several of the risk factors associated with the development of hypertrophy exhibit sexual dimorphism in their distribution in the general population. These sex-specific differences in risk factor distribution are likely important modifiers in disease progression and outcome. This review explores the available evidence of sex-specific differences in the evolution of left ventricular hypertrophy.
Related Concept Videos
Heart Failure II: Pathophysiology
Cellular Adaptation II: Hypertrophy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Pathophysiology of Heart Failure
Mitral Regurgitation I: Introduction

