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Updated: Aug 14, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Clozapine-induced tardive dyskinesia: a case report
Aygun Ertugrul1, Basaran Demir
1Department of Psychiatry, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey. aertugru@hacettepe.edu.tr
Purpose:
Clozapine is indicated in the treatment of patients with tardive dyskinesia. However, there have been some reports of movement disorders associated with clozapine treatment in the literature. The authors report a patient who developed tardive dyskinesia 1 year after initiation of clozapine treatment.
Case:
The patient was a 65-year-old male with diagnosis of schizophrenia who had used multiple typical and atypical antipsychotics for 30 years. Clozapine treatment was initiated for his resistant symptoms. He developed buccolingual dyskinesia of moderate severity, which started 1 year after the initiation of clozapine treatment and did not ameliorate during follow-up.
Conclusion:
This case may contribute to existing knowledge by raising the possibility that clozapine can induce dyskinesia.
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