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Long-term results of mitral valve repair in active endocarditis
Rachid Zegdi1, Mohamed Debièche, Christian Latrémouille
1René Descartes University, Paris, France.
Background:
Several investigators have reported the feasibility of mitral valve repair in active endocarditis, but the long-term results are still unknown.
Methods And Results:
We reviewed 37 consecutive patients who underwent mitral valve repair with the Carpentier technique for active endocarditis in our center between 1989 and 1994. This repair involved prosthetic annuloplasty in 31 patients (84%), valve resection in 31 (84%), chordal shortening or transposition in 19 (51%), pericardial patch in 16 (43%), and direct suture of leaflet perforation in 4 (11%). Associated procedures were primarily aortic valve repair or replacement in 11 (30%) and tricuspid repair in 2 (6%). Early complications included 1 operative death (3%; 95% CI, 0 to 15.5) and 1 reoperation for pericardial patch dehiscence. Recurrence of endocarditis was observed in 1 patient (3%; 95% CI, 0 to 16). The 10-year survival rate and freedom from mitral valve reoperation were 80% (95% CI, 66 to 94) and 91% (95% CI, 81 to 100), respectively. At 10 years, most patients (96%) were in good functional status (NYHA class I to II) with no or trivial mitral regurgitation (92%) on echocardiography.
Conclusions:
Mitral valve repair using Carpentier's techniques in patients with active endocarditis offers very good long-term results with a low rate of recurrence or reoperation.
Insights
Mitral valve repair for active endocarditis using Carpentier techniques shows excellent long-term outcomes. This surgical approach provides high survival and low reoperation rates, with most patients maintaining good function.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Cardiac Valve Repair
Background:
- Long-term results of mitral valve repair in active endocarditis remain largely unknown.
- Previous studies reported feasibility but lacked long-term outcome data.
Purpose of the Study:
- To evaluate the long-term efficacy and safety of mitral valve repair for active endocarditis.
- To assess survival, reoperation rates, and functional status post-repair.
Main Methods:
- Retrospective review of 37 patients undergoing mitral valve repair with the Carpentier technique for active endocarditis (1989-1994).
- Detailed analysis of repair techniques, associated procedures, early complications, and long-term outcomes.
- Evaluation included survival, mitral valve reoperation, functional status (NYHA class), and echocardiographic assessment of mitral regurgitation.
Main Results:
- The 10-year survival rate was 80%, with 91% freedom from mitral valve reoperation.
- 96% of patients were in good functional status (NYHA class I-II) at 10 years.
- 92% had no or trivial mitral regurgitation on echocardiography; recurrence of endocarditis was low (3%).
Conclusions:
- Mitral valve repair using Carpentier techniques in active endocarditis yields very good long-term results.
- The procedure is associated with a low rate of endocarditis recurrence and reoperation.
- This approach offers a durable solution for patients with active endocarditis requiring mitral valve intervention.
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