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[Decline of cognitive capacity during aging].
Helenice Charchat-Fichman1, Paulo Caramelli, Koichi Sameshima
1Departamento de Neurologia, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil. hcharchat@uol.com.br
Summary
Normal aging or pre-dementia can cause cognitive decline. Elderly individuals experiencing cognitive decline, particularly with memory issues, face a higher risk of developing Alzheimer's disease.
Area of Science:
- Gerontology
- Neurology
- Cognitive Science
Context:
- Cognitive decline is a common concern in aging populations.
- Epidemiological studies link cognitive decline to increased Alzheimer's disease risk.
- Episodic memory deficits are a key indicator in at-risk individuals.
Purpose:
- To review diagnostic criteria for cognitive decline in aging.
- To summarize neuropathological findings associated with cognitive decline.
- To present neuropsychological findings relevant to aging and cognitive capacity.
Summary:
- This review examines the multifaceted nature of cognitive decline during aging.
- It differentiates between age-related cognitive changes and pre-dementia stages.
- Key diagnostic, neuropathological, and neuropsychological aspects are discussed.
Impact:
- Provides a comprehensive overview for understanding cognitive aging.
- Highlights the link between cognitive decline and Alzheimer's disease risk.
- Informs clinical assessment and research into cognitive impairment.