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Related Experiment Videos

Relapsing polychondritis with aortitis without valvular involvement.

Young Hee Rho1, Seong Jae Choi, Youn Seon Choi

  • 1Division of Rheumatology, Korea University Guro Hospital, Seoul, South Korea.

The Journal of Rheumatology
|May 4, 2005
PubMed
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Relapsing polychondritis can affect the cardiovascular system, leading to serious complications. This case highlights successful treatment of aortitis in a patient with relapsing polychondritis using corticosteroids and methotrexate.

Area of Science:

  • Rheumatology
  • Cardiology
  • Internal Medicine

Background:

  • Relapsing polychondritis is a rare multisystemic autoimmune disorder of unknown cause.
  • It primarily affects cartilaginous structures, but cardiovascular involvement can lead to significant morbidity and mortality.
  • Aortic root dilation and regurgitation are the most common cardiovascular manifestations.

Observation:

  • A 51-year-old Korean woman presented with relapsing polychondritis and aortitis.
  • Notably, she did not exhibit aortic valve involvement.
  • Her primary symptom was abdominal pain.

Findings:

  • The study details the first reported case in Korea of relapsing polychondritis with aortitis without aortic valve involvement.
  • The patient's aortitis presented with atypical symptoms of abdominal pain.

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Implications:

  • This case expands the understanding of cardiovascular manifestations in relapsing polychondritis.
  • It suggests that aortitis can occur without aortic valve involvement and present with unusual symptoms.
  • Successful management with corticosteroids and methotrexate was demonstrated, offering potential therapeutic insights.