Related Experiment Video
Updated: Aug 18, 2026

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
Cerebral infarction associated with possible enteroviral infection in an infant
Wen-Hsin Tsai1, Wang-Tso Lee, Chun-Yi Lu
1Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Abstract:
Enterovirus infection has been rarely reported to cause cerebral infarction in infants. We describe a 2-month-old boy with right focal seizure and right hemiparesis associated with enterovirus infection during an epidemic of enterovirus 71 infection in Taiwan in 1998. Magnetic resonance imaging and angiography showed vasculitis in the left anterior cerebral artery with cerebral infarction. In the unclarified pathogenesis of cerebral disease in enterovirus infection, this case suggests focal vasculitis with subsequent cerebral infarction. Enterovirus-related vasculitis of the central nervous system is thus another consideration when facing a child with focal seizure, acute hemiplegia and cerebral infarction.
Insights
Enterovirus infection can rarely cause cerebral infarction in infants. This case highlights enterovirus-induced vasculitis leading to stroke in a young child.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Enterovirus infections are uncommon causes of cerebral infarction in infants.
- Cerebral infarction in infants presents a diagnostic challenge, particularly when linked to viral etiologies.
Observation:
- A 2-month-old infant presented with focal seizures and hemiparesis during an enterovirus 71 epidemic.
- Neuroimaging revealed vasculitis of the left anterior cerebral artery and subsequent cerebral infarction.
Findings:
- This case suggests a link between enterovirus infection and focal vasculitis affecting the central nervous system.
- The findings indicate that enterovirus-related vasculitis can lead to cerebral infarction in infants.
Implications:
- Enterovirus-induced vasculitis should be considered in the differential diagnosis of acute hemiplegia and cerebral infarction in children.
- Further research is needed to elucidate the pathogenesis of enterovirus-related central nervous system diseases.
Related Concept Videos
Viral Meningitis
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Arboviral Encephalitis
Poliomyelitis
Cytomegalovirus Disease

