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Updated: Jul 15, 2026

Synthesis and Catalytic Performance of Gold Intercalated in the Walls of Mesoporous Silica
Published on: July 9, 2015
Thiolate ligands for synthesis of water-soluble gold clusters
Christopher J Ackerson1, Pablo D Jadzinsky, Roger D Kornberg
1Department of Structural Biology, Stanford University, 299 Campus Drive West, Stanford, CA 94305, USA.
Abstract:
Water-soluble monolayer-protected gold clusters (MPCs) have been an object of investigation by many research groups since their first syntheses were reported in 1998 and 1999. The basic requirements for a ligand to form a monolayer protecting a gold cluster were established some time ago for alkanethiolate MPCs, but there has been no such information published for water-soluble MPCs. We identify 6 new ligands capable of forming water-soluble MPCs, as well as 22 water-soluble ligands that fail to form MPCs. Our findings contribute not only to the definition of the requirements for MPC formation but also to the variety of MPCs available for applications in chemistry and biology.
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