Mathematical methods relevant to the study of wound healing

Over recent years there has been a growing interest in the application of mathematical techniques and methods to improve understanding of clinical problems. Mathematical methods permit accurate description and quantification of observations and processes. Wound healing is a clinical problem that needs support in order to improve management and understanding of the mechanisms that may disarrange healing processes. This article attempts to provide an overview of currently available methods that have a direct relevance to the management of lower extremity wounds. Mathematics can provide valuable assistance and insight to clinical understanding, but only if applied correctly. It is hoped that examples of good practice will promote the utilization of this versatile tool.