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Leukemia following cisplatin-based chemotherapy for ovarian carcinoma at Roswell Park
H E Sprance1, R E Hempling, M S Piver
1Department of Gynecologic Oncology Roswell Park Cancer Institute, Buffalo, New York.
European Journal of Gynaecological Oncology
|January 1, 1992
Abstract:
Three cases of leukemia following cisplatin-based chemotherapy are reported. All three patients received cyclophosphamide, a known leukemogen. In two cases, the leukemia was diagnosed after second line chemotherapy with intraperitoneal cisplatin and cytarabine, one of which is the first report of a chronic granulocytic leukemia as a result of cytotoxic chemotherapy.