Related Experiment Video
Updated: Aug 18, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
Synthesis and structure of cerium-substituted hydroxyapatite
Zude Feng1, Yingmin Liao, Meng Ye
1Department of Materials Science and Engineering, State Key Laboratory of Physical Chemistry at the Solid Surfaces, Xiamen University, Xiamen 361005, China. zdfeng@xmu.edu.cn
Abstract:
The aim of this study was to explore the effect of cerium ions on the formation and structure of hydroxyapatite (HAP). All particles, prepared by hydrothermal method, were synthesized at varied X(Ce) = Ce/(Ca + Ce) (from 0 to 10%) with the atomic ratio (Ce + Ca)/P fixed at 1.67. Their morphology, composition and crystal structure were characterized by TEM, EPMA, XRD and FTIR. The results showed that in this composition range the apatite structure is maintained, Ce3+ ions could enter the crystal lattice of apatite and substitute Ca2+ ions. The doping of Ce3+ ions resulted in the decrease of the crystallite size with increase in X(Ce). The HAP particles without doping were short rods having a diameter from 10 to 20 nm and a length from 30 to 50 nm. They grew into long needles upon increasing X(Ce).
Related Concept Videos
Hydration of Cement
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Ionic Compounds: Formulas and Nomenclature
The Bone Matrix
Imperfections in Crystal Structure: Non-Stoichiometric Defects
Strength and Heat of Hydration
The heat of hydration for each cement compound is significant; for instance, tricalcium aluminate (C3A) and...

