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Renoprotective effect of grape seeds extract in ethylene glycol induced nephrotoxic mice
M Mohanasundari1, M Sabesan, S Sethupathy
1Department of Zoology, Rajah Muthiah Medical College, Annamalai University, Annamalai Nagar, India.
Indian Journal of Experimental Biology
|May 7, 2005
Abstract:
Grape seed extract treatment in ethylene glycol (EG) induced nephrotoxic mice improved antioxidant status and significantly decreased urinary lactate dehydrogenase (LDH) and lipid peroxidation. The extract rendered antioxidant protection against oxidative stress induced by EG and may help in protecting renal tissue against EG toxicity.
