Acids direct 2-styrylcyclobutanone into two distinctly different reaction pathways
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Updated: Aug 18, 2026

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
Published on: November 9, 2019
Masahiro Murakami1, Sho Kadowaki, Atsushi Fujimoto
1Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Katsura, Japan. murakami@sbchem.kyoto-u.ac.jp
Abstract:
Two structurally distinct carbocycles were selectively obtained by the reactions of 2-(o-styryl)cyclobutanones promoted by ytterbium salts. Treatment of the cyclobutanones with YbCl(3) in 1,4-dioxane at 100 degrees C afforded 2-(2-chloroethyl)naphthalenes. On the other hand, the reaction with Yb(OTf)(3) in chlorobenzene at 130 degrees C gave 9,10-dihydrobenzocycloocten-7(8H)-ones.
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