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Updated: Aug 18, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Amebic liver abscesses among neonates can mimic bacterial sepsis
Zafar Nazir1, Saqib Hamid Qazi
1Section of Pediatric Surgery, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan. zafar.nazir@aku.edu
Abstract:
Amebic liver abscesses are unusual among neonates. Three (3.6%) of 83 children who presented to a university hospital with amebic liver abscesses in a 17-year period were neonates (<28 days of age). Patients presented with nonspecific clinical and laboratory findings mimicking fulminant neonatal sepsis. Diagnosis was delayed and was based on the presence of a hypoechoic lesion in the liver, antibodies against Entamoeba histolytica and microbiologic examination of pus. In addition to parenteral metronidazole treatment and early ultrasound-guided aspiration of the abscess, intensive care is vital for the treatment of neonates with amebic liver abscesses.
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