Related Experiment Video
Updated: Aug 18, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Heart and periodontal diseases: does evidence exist of association?
Gema Jiménez-Beato1, Guillermo Machuca-Portillo
1Clínica Odontológica Integrada de Pacientes Especiales, Facultad de Odontología de Sevilla, Universidad de Sevilla, Sevilla.
Insights
Periodontal disease may be linked to cardiovascular diseases, a major cause of death. Further research is needed to confirm if this oral health condition is a definitive risk factor for heart disease.
Area of Science:
- Cardiology
- Periodontology
- Public Health
Background:
- Cardiovascular diseases (CVDs) are a leading cause of mortality globally.
- Early detection of CVD risk factors is crucial for prevention.
- Periodontal diseases are highly prevalent and may be associated with CVDs.
Purpose of the Study:
- To review the clinical and physiopathological factors supporting the association between periodontal pathology and cardiovascular diseases.
- To evaluate the potential of periodontal disease as a risk factor for CVDs.
Main Methods:
- Literature review of clinical and physiopathological studies.
- Analysis of scientific evidence linking oral health and cardiovascular health.
Main Results:
- The review identified potential links between periodontal pathology and cardiovascular diseases.
- The prevalence of periodontal diseases suggests clinical and epidemiological significance.
Conclusions:
- While evidence suggests an association, further studies are required.
- Definitive proof is needed to establish periodontal disease as a confirmed risk factor for cardiovascular diseases.
Abstract:
Cardiovascular diseases represent one of the main causes of death in developed societies. These diseases are not only important because of the mortality they generate, but also due to the high number of affected persons under treatment that the health systems of different countries have to support. Hence, the early detection of risk factors triggering these diseases has been seen as the most effective mechanism to prevent them. Over the last few years periodontal pathology has been more or less related to the suffering of cardiovascular diseases. This fact could be of great clinical and epidemiological relevance owing to the actual considerable prevalence of periodontal diseases. In the present review, the clinical and physiopathological factors which scientifically support this association are analyzed,reaching the conclusion that further studies are needed to have the proof that said association represents a determinate risk factor for the suffering of cardiovascular diseases.
Related Concept Videos
The Oral Microbiota
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Rheumatic Heart Disease I: Introduction
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease I: Introduction
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
