Heart and periodontal diseases: does evidence exist of association?

Gema Jiménez-Beato1, Guillermo Machuca-Portillo

  • 1Clínica Odontológica Integrada de Pacientes Especiales, Facultad de Odontología de Sevilla, Universidad de Sevilla, Sevilla.

Insights

Periodontal disease may be linked to cardiovascular diseases, a major cause of death. Further research is needed to confirm if this oral health condition is a definitive risk factor for heart disease.

Area of Science:

  • Cardiology
  • Periodontology
  • Public Health

Background:

  • Cardiovascular diseases (CVDs) are a leading cause of mortality globally.
  • Early detection of CVD risk factors is crucial for prevention.
  • Periodontal diseases are highly prevalent and may be associated with CVDs.

Purpose of the Study:

  • To review the clinical and physiopathological factors supporting the association between periodontal pathology and cardiovascular diseases.
  • To evaluate the potential of periodontal disease as a risk factor for CVDs.

Main Methods:

  • Literature review of clinical and physiopathological studies.
  • Analysis of scientific evidence linking oral health and cardiovascular health.

Main Results:

  • The review identified potential links between periodontal pathology and cardiovascular diseases.
  • The prevalence of periodontal diseases suggests clinical and epidemiological significance.

Conclusions:

  • While evidence suggests an association, further studies are required.
  • Definitive proof is needed to establish periodontal disease as a confirmed risk factor for cardiovascular diseases.

Related Concept Videos

The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...