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Related Experiment Videos

The sinus lift with phycogenic bone substitute. A histomorphometric study.

Antonin Simunek1, Michal Cierny, Dana Kopecka

  • 1Department of Stomatology, Faculty of Medicine in Hradec Kralove, Charles University in Prague, 500-05 Hradec Kralove, Czech Republic. simunek_antonin@email.cz

Clinical Oral Implants Research
|May 10, 2005
PubMed
Summary

Phycogenic bone substitute effectively promotes new bone growth in sinus lifts, showing gradual resorption and replacement by quality bone over 15 months. This method offers limited invasiveness and a high implant survival rate.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Regenerative Medicine
  • Biomaterials Science

Background:

  • Sinus floor augmentation is crucial for dental implant placement in the posterior maxilla.
  • Grafting materials are essential for successful sinus lifts, aiming for predictable bone regeneration.
  • Phycogenic bone substitutes offer a novel option for sinus augmentation.

Purpose of the Study:

  • To evaluate the efficacy of a phycogenic bone substitute (fluorohydroxyapatite) in sinus lifts.
  • To histomorphometrically assess graft healing, bone remodeling, and biomaterial replacement.
  • To compare one-stage versus two-stage sinus lift procedures using this material.

Main Methods:

  • Prospective histomorphometric study involving 24 sinus lift procedures using phycogenic material.

Related Experiment Videos

  • Placement of 45 titanium implants, with follow-up of 12-23 months.
  • Histomorphometric analysis of 24 graft specimens harvested at 6, 9, 12, or 15 months post-surgery.

    • Main Results:

    • Phycogenic material was gradually resorbed and replaced by newly formed bone.
    • New bone formation increased linearly from 15.5% to 40.8% between 6 and 15 months.
    • Bone substitute decreased linearly from 34.5% to 13% during the same period; trabecular density reached cancellous bone quality by 15 months.
    • No significant difference in new bone quality was observed between one-stage and two-stage procedures.

    Conclusions:

    • Sinus lifts using phycogenic bone substitute are effective, demonstrating good bone regeneration and remodeling.
    • The biomaterial shows gradual resorption and replacement, contributing to high-quality bone formation.
    • The procedure is minimally invasive with a high implant survival rate of 97.8%.