Related Experiment Video
Updated: Aug 18, 2026

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
Diastolic heart failure: a review and primary care perspective
Sean Haney1, Denise Sur, Zijian Xu
1Department of Family Medicine, Division of Sports Medicine, Kaiser Permanente, Los Angeles, California 90027, USA. sean.x.haney@kp.org
Insights
Diastolic heart failure (DHF) is now recognized as a distinct condition, particularly common in the elderly and carrying significant health burdens. Evidence-based management strategies are crucial for primary care physicians treating DHF.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Diastolic heart failure (DHF) is now a recognized distinct entity.
- DHF is highly prevalent, especially in elderly populations, often exceeding systolic heart failure (SHF) incidence.
- Both DHF and SHF contribute to substantial morbidity, mortality, and healthcare costs.
Purpose of the Study:
- To review the current understanding of diastolic heart failure.
- To emphasize evidence-based management approaches for DHF.
- To provide guidance for primary care physicians managing DHF patients.
Main Methods:
- Review of existing literature on DHF pathophysiology and treatment.
- Analysis of clinical trial data, though limited for isolated DHF.
- Synthesis of current concepts and clinical experience in DHF management.
Main Results:
- Consensus confirms DHF as a distinct heart failure type.
- DHF is epidemiologically significant, particularly in older adults.
- Treatment primarily relies on pathophysiology understanding and SHF experience due to limited DHF-specific trials.
Conclusions:
- DHF diagnosis is primarily clinical, with limited supporting data.
- Prognosis and treatment differ between diastolic and systolic heart failure.
- This review focuses on evidence-based management for primary care physicians.
Abstract:
Previously the subject of much debate, there is now consensus that diastolic heart failure (DHF) represents a distinct form of heart failure. Epidemiologic data indicate that DHF is common. Indeed, there is evidence that, among elderly persons, DHF is more common than systolic heart failure (SHF). Like SHF, DHF is associated with significant morbidity, mortality, and cost; however, few clinical trials focusing on isolated DHF have been completed. Much of the treatment of DHF is based on current concepts of the pathophysiology of DHF, small clinical studies, and experience gained from treating patients with SHF. The diagnosis of DHF is clinical; data supporting the establishment of a diagnosis of DHF are limited. Differences exist in prognosis and treatment between diastolic and systolic heart failure. This article reviews diastolic heart failure with emphasis on evidence-based management, aimed at primary care physicians who routinely provide care to patients with DHF.
Related Concept Videos
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure V: Medical Management
Heart Failure II: Pathophysiology
Cardiomyopathy V: Interprofessional Care
Heart Failure VII: Nursing Interventions
Rheumatic Heart Disease III: Medical Management
