[Primary cardiac angiosarcoma in the left atrium with adrenal metastasis; report of a case]

Fumiaki Kuwabara1, Y Hirate, T Sugiura

  • 1Department of Cardiovascular Surgery, Nagoya Ekisaikai Hospital, Nagoya, Japan.

Insights

A rare primary cardiac angiosarcoma in the left atrium led to significant mitral valve issues. Despite initial resection, the cancer metastasized to the adrenal gland and recurred, ultimately causing heart failure.

Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Primary cardiac angiosarcoma is a rare and aggressive malignancy.
  • Left atrial angiosarcoma can significantly impact cardiac function, particularly the mitral valve.

Observation:

  • A 61-year-old woman presented with a left atrial angiosarcoma involving the mitral valve, causing stenosis and regurgitation.
  • Initial surgical resection improved mitral valve function postoperatively.
  • Three months later, adrenal metastasis and left atrial recurrence were detected, alongside worsening mitral valve disease.

Findings:

  • Cardiac angiosarcoma can metastasize to distant organs, such as the adrenal glands.
  • Recurrence of angiosarcoma in the left atrium can lead to progressive mitral valve dysfunction.
  • The patient succumbed to heart failure 185 days postoperatively due to disease progression.

Implications:

  • Early detection and aggressive management are crucial for primary cardiac angiosarcoma.
  • Metastatic spread and recurrence pose significant challenges in managing this condition.
  • Multidisciplinary approaches are essential for optimizing patient outcomes in rare cardiac tumors.

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