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The apparent inversion time for optimal delayed enhancement magnetic resonance imaging differs between the right and

Milind Y Desai1, Sandeep Gupta, Chandra Bomma

  • 1Division of Cardiology, Johns Hopkins University, Baltimore, Maryland 21287, USA.

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
|May 11, 2005
PubMed
Abstract

Insights

The inversion time (TI) for optimal signal suppression differs between the left and right ventricles in cardiac MRI. This finding may be due to variations in RV blood pool or trabeculation, impacting image interpretation.

Area of Science:

  • Cardiovascular Imaging
  • Magnetic Resonance Imaging
  • Cardiac Anatomy

Background:

  • Delayed post-contrast MRI uses specific inversion times (TI) for myocardial signal suppression, making scar tissue visible.
  • A discrepancy was observed where the right ventricle (RV) appeared brighter than the left ventricle (LV) at the TI optimized for LV signal suppression.

Purpose of the Study:

  • To evaluate the optimal inversion time (TI) for signal suppression in the RV compared to the LV.
  • To investigate the underlying causes for the observed differences in signal suppression between the ventricles.

Main Methods:

  • Studied 31 patients using a 1.5 T GE scanner with delayed post-contrast sequences.
  • Acquired short-axis images 20 minutes after gadolinium injection.
  • Optimized TI by acquiring a range of times within a single breath-hold to determine the lowest signal for both RV and LV.

Main Results:

  • The TI for LV signal suppression ranged from 150-225 ms.
  • At the LV-optimized TI, RV signal was significantly higher (29 +/- 13 au) than LV signal (15 +/- 8 au, p < 0.001).
  • The TI required for RV signal suppression was typically <=150 ms, with findings consistent across imaging coils and pre/post-contrast.

Conclusions:

  • The optimal inversion time (TI) for myocardial signal suppression varies between the LV and RV.
  • Potential explanations include partial volume effects from increased RV trabeculation or blood pool.
  • Differences in RV blood pool signal intensity may also influence TI, potentially due to Thebesian veins or arterioluminal communications.

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