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Sacro-iliac joint scanning with technetium-99 diphosphonate.

M Lugon, A S Torode, R L Travers

    Rheumatology and Rehabilitation
    |August 1, 1979
    PubMed
    Summary

    Quantitative sacro-iliac joint scanning using technetium-99m methylene diphosphonate (99TcMDP) shows elevated uptake in active ankylosing spondylitis but also in some patients with low back pain. Caution is needed when interpreting these bone scans.

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    Arthritis and rheumatism·1998

    Area of Science:

    • Nuclear Medicine
    • Rheumatology
    • Radiology

    Background:

    • Radio-isotope bone scanning offers quantitative assessment of joint inflammation.
    • Previous studies highlight its utility in early sacro-iliitis detection.
    • Quantitative sacro-iliac (SI) joint scanning with 99TcMDP is explored for evaluating SI disease.

    Purpose of the Study:

    • To evaluate sacro-iliac disease using quantitative SI joint scans.
    • To assess the diagnostic utility of 99TcMDP scans in various low back pain patient groups.

    Main Methods:

    • Quantitative SI joint scans performed using 99TcMDP.
    • Patient groups included controls, ankylosing spondylitis, mechanical low back pain, and seronegative arthritis.
    • Radio-isotope index was calculated and compared across groups.

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    Main Results:

    • Elevated 99TcMDP uptake (index > 1.5) observed in active ankylosing spondylitis.
    • Some seronegative arthritis patients (HL-A B27 positive) and mechanical low back pain patients showed elevated uptake.
    • Elevated uptake in mechanical low back pain was unassociated with B27.

    Conclusions:

    • Interpretation of abnormal SI joint scans requires caution due to non-specific findings.
    • Quantitative bone scanning can assess inflammatory activity but needs careful correlation with clinical and other diagnostic data.
    • Findings suggest potential for false positives in SI joint scans for low back pain patients without inflammatory arthritis.