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Updated: Jul 24, 2026

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Endometrial adenocarcinoma presenting in a premenopausal patient with tuberous sclerosis
1Sharon Hospital, Sharon, CT 06069, USA. jjaffe@snet.net
Background:
Endometrial adenocarcinoma is very uncommon in women under 40 years of age.
Case:
A 39-year-old woman with tuberous sclerosis and severe intellectual disability presented with irregular bleeding unresponsive to oral contraceptive therapy. She was subsequently found to have a deeply invasive endometrial adenocarcinoma.
Conclusion:
Caregivers must pay particular attention to signs and symptoms in non-verbal patients. Persistent irregular bleeding on oral contraceptive therapy warrants additional evaluation.
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