Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Solid-state phase behaviour of dodecylglycosides.

Caroline A Ericsson1, Louise C Ericsson, Stefan Ulvenlund

  • 1Department of Physical Chemistry 1, Centre of Chemistry and Chemical Engineering, Lund University, Sweden.

Carbohydrate Research
|May 11, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Excipient effect on phenol-induced precipitation of human growth hormone and bovine serum albumin.

International journal of pharmaceutics·2025
Same author

Exploiting spatial isomerism to modulate the assembled phase and rheological response of compositionally identical sugar-based surfactants.

Chemical science·2025
Same author

An integrative toolbox to unlock the structure and dynamics of protein-surfactant complexes.

Nanoscale advances·2022
Same author

Topological Dynamics of Micelles Formed by Geometrically Varied Surfactants.

Langmuir : the ACS journal of surfaces and colloids·2022
Same author

Shear-induced nanostructural changes in micelles formed by sugar-based surfactants with varied anomeric configuration.

Journal of colloid and interface science·2021
Same author

Tail unsaturation tailors the thermodynamics and rheology of a self-assembled sugar-based surfactant.

Journal of colloid and interface science·2020
Same journal

Preparation of fucose-containing galacto-oligosaccharides using a commercial β-galactosidase from Bifidobacterium bifidum.

Carbohydrate research·2026
Same journal

Two distinct sulfated O-polysaccharides from the marine bacterium Vibrio sp. KMM 9700: Genomic prediction and structural elucidation.

Carbohydrate research·2026
Same journal

Binding evaluation of poacic acid for fungal cell-wall glycans and β-1,3-glucooligosaccharides.

Carbohydrate research·2026
Same journal

Chemoenzymatic synthesis of unusual antibody glycoforms using E. coli expressed human and bovine β-1,4-galactosyltransferase and their mutants.

Carbohydrate research·2026
Same journal

Bioactive 13,28-oxidooleanane-type saponins from Measa kamerunensis Merk.

Carbohydrate research·2026
Same journal

Stereoselective synthesis of 1,2-annulated C-glycosides via palladium-catalyzed intramolecular annulation of C-aryl glycosides.

Carbohydrate research·2026
See all related articles

Lyophilization of alkylglycosides yields different solid-state behaviors: n-dodecyl-beta-D-glucoside forms a crystalline anhydrate, while longer chain variants form glassy states. Control of water content is crucial for analyzing alkylglycoside phase behavior.

Area of Science:

  • Materials Science
  • Physical Chemistry
  • Biochemistry

Background:

  • Alkylglycosides are amphiphilic molecules with applications in various fields.
  • Understanding their solid-state phase behavior is essential for formulation and processing.
  • Lyophilization is a common drying technique that can significantly impact molecular structure.

Purpose of the Study:

  • To investigate the solid-state phase behavior of lyophilized n-dodecyl-beta-D-glucoside (beta-C(12)G(1)), n-dodecyl-beta-D-maltoside (beta-C(12)G(2)), and n-dodecyl-beta-D-maltotrioside (beta-C(12)G(3)).
  • To elucidate the influence of alkyl chain length and glycosidic linkage on the resulting solid-state forms.
  • To correlate structural characteristics with thermal properties.

Main Methods:

  • Differential Scanning Calorimetry (DSC) for thermal analysis.

Related Experiment Videos

  • X-ray diffraction techniques to determine lamellar spacing and structural arrangements.
  • Controlled drying and re-crystallization experiments.

    • Main Results:

    • Lyophilized beta-C(12)G(1) formed a crystalline anhydrate with non-interdigitated alkyl chains.
    • Lyophilized beta-C(12)G(2) and beta-C(12)G(3) formed glassy states, representing frozen lamellar liquid crystals with interdigitated alkyl chains.
    • Glass transition temperatures were observed at 65°C for beta-C(12)G(2) and 100°C for beta-C(12)G(3).

    Conclusions:

    • The solid-state phase behavior of lyophilized alkylglycosides is dependent on the carbohydrate headgroup size.
    • A second crystalline form of beta-C(12)G(1) with interdigitated chains was identified.
    • Water content critically influences the phase behavior and analysis of alkylglycosides.