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Updated: Jul 25, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 27, 2013
Early phase combined therapeutic management of acute ischaemic stroke
P Bassi1, P Lattuada, S Tonietti
1Neurological Department, San Carlo Borromeo Hospital, Via Pio II 3, I-20153 Milan, Italy. bassi.pietro@sancarlo.mi.it
Abstract:
An adequate treatment of ischaemic stroke in the early phase (28-48 h) is the most important factor for a better outcome. Thrombolysis with rTPA (within 3 h) and oral ASA 300 mg/days are the first therapeutic misures. Continuous monitoring of cardiological and haemodinamic parameters allows early detection of cardiac disturbances. Treatment of hypertension, low haematic oxigenation, hyperglicaemia, seizures and hypertermia is basic to improve outcome. Pharmacological therapy is only one of the components of effective multidisciplinary integrated management of ischaemic stroke; we remind also the precocity of rehabilitation procedures and an accurate psychological assessment.
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