Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Synaptic integration in dendritic trees.

Allan T Gulledge1, Björn M Kampa, Greg J Stuart

  • 1Division of Neuroscience, John Curtin School of Medical Research, The Australian National University, Canberra.

Journal of Neurobiology
|May 11, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Environmental Context Modulates Habituation of Visually Evoked Defensive Behavior.

eNeuro·2026
Same author

Non-reciprocal callosal projections and input gradients underlie interhemispheric communication in binocular visual cortex.

Cell reports·2026
Same author

Lack of cross modal plasticity potentially linked to ongoing activation of visual cortex and superior colliculus in the rd10 mouse model of retinitis pigmentosa.

Cerebral cortex (New York, N.Y. : 1991)·2025
Same author

Biologically grounded neocortex computational primitives implemented on neuromorphic hardware improve vision transformer performance.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Afferent-specific modulation of excitatory synaptic transmission by acetylcholine and serotonin in the prelimbic cortex.

bioRxiv : the preprint server for biology·2025
Same author

Broadband visual stimuli improve neuronal representation and sensory perception.

Nature communications·2025
Same journal

The molecular receptive range of an olfactory receptor in vivo (Drosophila melanogaster Or22a).

Journal of neurobiology·2006
Same journal

Consistent dynamics suggests tight regulation of biophysical parameters in a small network of bursting neurons.

Journal of neurobiology·2006
Same journal

Early condition, song learning, and the volume of song brain nuclei in the zebra finch (Taeniopygia guttata).

Journal of neurobiology·2006
Same journal

L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord.

Journal of neurobiology·2006
Same journal

Singing, but not seizure, induces synaptotagmin IV in zebra finch song circuit nuclei.

Journal of neurobiology·2006
Same journal

Developmental regulation of sensory axon regeneration in the absence of growth cones.

Journal of neurobiology·2006
See all related articles

Neurons integrate thousands of synaptic inputs via dendritic trees. Active conductances in dendrites shape these inputs, influencing neuronal excitability and synaptic integration.

Area of Science:

  • Neuroscience
  • Cellular Neuroscience

Background:

  • Neurons possess complex dendritic trees receiving numerous synaptic inputs.
  • Individual synaptic events are typically small, necessitating integration for neuronal depolarization.

Purpose of the Study:

  • To review how active and passive dendritic properties influence synaptic integration in central neurons.
  • To highlight the role of dendritic ion channels in shaping neuronal responses.

Main Methods:

  • Review of recent advances in electrical and optical recording techniques.
  • Analysis of studies investigating synaptic response propagation and interaction in dendrites.

Main Results:

  • Dendrites exhibit active conductances (e.g., voltage-gated Na+, Ca2+, K+ channels) that modulate synaptic responses.

Related Experiment Videos

  • These active properties, alongside passive properties, shape synaptic integration locally within dendrites.
  • Specific patterns of dendritic channel expression lead to cell-type-specific synaptic integration.

    • Conclusions:

    • Active dendritic properties are crucial for shaping synaptic responses and neuronal integration.
    • Dendritic ion channels play a key role in regulating neuronal excitability and information processing.
    • Understanding dendritic integration is vital for comprehending central neuron function.