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Updated: Aug 18, 2026
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Combining Single-molecule Manipulation and Imaging for the Study of Protein-DNA Interactions
Published on: August 27, 2014
Single-molecule manipulation measurements of DNA transport proteins
Omar A Saleh1, Jean-François Allemand, Vincent Croquette
1Laboratoire de Physique Statistique et Département de Biologie, Ecole Normale Supérieure, UMR8550 associé au CNRS et aux Université Paris VI, Paris, France.
Abstract:
Single-molecule measurements of the manipulation of three different DNA motor proteins are reviewed. Despite some differences in the structure and mechanisms of the proteins, there are consistent phenomenological themes that relate them. Each of the experiments described represents a significant advance in the understanding of the mechanisms of DNA transport.
