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Localization of single avidin-biotin interactions using simultaneous topography and molecular recognition imaging

Andreas Ebner1, Ferry Kienberger, Gerald Kada

  • 1Institute of Biophysics, University of Linz, 4040 Linz, Austria.

Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry
|May 11, 2005
PubMed
Abstract

No abstract available in PubMed .

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...

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