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Updated: Aug 18, 2026

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
Published on: November 6, 2019
Does topical lidocaine with adrenaline have an effect on morbidity in pediatric tonsillectomy?
E Egeli1, U Harputluoglu, F Oghan
1University of Abant Izzet Baysal, Düzce Faculty of Medicine, Department of Otorhinolaryngology-Head and Neck Surgery, Düzce, Turkey.
Objective:
To evaluate the efficacy of lidocaine with adrenaline on post-operative morbidity in pediatric patients after tonsillectomy.
Study Design:
A double blind prospective randomized controlled clinical study.
Methods:
The study is consisting of two groups of pediatric patients following tonsillectomy performed in a university hospital. One group received lidocaine with adrenaline soaked swabs packed in their tonsillar fossae while the control group received saline-soaked swabs. Chi-square and two-tailed unpaired Student's t-tests were used to compare the two independent groups. p<0.05 was accepted as statistically significant.
Results:
No significant pain-relieving effect was seen in the lidocaine with adrenaline group (p>0.05) and also the other post-operative parameters such as nausea, fever, vomiting, odor, bleeding, otalgia and trismus were not statistically different between the two groups based on chi-square analysis (p>0.05). There were no complications associated with lidocaine and adrenaline.
Conclusion:
We suggest that application of topical lidocaine with adrenaline seems to be a safe and easy medication for local anesthetic use. However, in our study, lidocaine with adrenaline offered no advantage over placebo in the control of post-operative pain and other morbidity related factors following pediatric tonsillectomy. We therefore do not recommend topical application of lidocaine with adrenaline for reducing morbidity in pediatric tonsil surgery.
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