Related Experiment Video
Updated: Aug 18, 2026
06:47
Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
No increase in CD62P-positive single platelets after acute platelet activation in vivo
Reinhard Voss1, Eberhard Morgenstern, Wolfgang Waas
1Center of Internal Medicine, Department of Cardiology/Angiology, Justus-Liebig-University Giessen, Germany. Reinhard.k.voss@innere.med.uni-giessen.de
Thrombosis Research
|May 12, 2005
Abstract
No abstract available in PubMed .
Related Concept Videos
01:22Formation of the Platelet Plug
The platelet phase, the second stage of hemostasis, commences around 15-20 seconds after an injury. It follows and overlaps with the vascular phase, during which blood vessels constrict to minimize blood loss.
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
As the injured blood vessel contracts, endothelial cells undergo contraction, revealing collagen fibers in the basement membrane and underlying connective tissue. Furthermore, the plasma membrane of endothelial cells becomes adhesive, preparing the site for platelet adhesion. Platelets...
01:16Clot Retraction and Fibrinolysis
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.