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Assessment of Child Anthropometry in a Large Epidemiologic Study
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Changes in growth pattern, body composition and biochemical markers of growth after adenotonsillectomy in prepubertal

Betül Ersoy1, Ali Vefa Yücetürk, Fatma Taneli

  • 1Celal Bayar University, Faculty of Medicine, Department of Pediatrics, Division of Pediatric Endocrinology, Manisa, Turkey. betul_e@hotmail.com

International Journal of Pediatric Otorhinolaryngology
|May 12, 2005
PubMed

Insights

Adenotonsillar hypertrophy (ATH) slows childhood growth. Adenotonsillectomy (A&T) in children with ATH accelerates growth, increasing weight and insulin-like growth factor-1 (IGF-1) levels, suggesting a rise in growth hormone (GH).

Area of Science:

  • Pediatric Endocrinology
  • Otolaryngology
  • Growth and Development

Background:

  • Adenotonsillar hypertrophy (ATH) can impede childhood growth.
  • Understanding growth dynamics post-adenotonsillectomy (A&T) is crucial for pediatric health.

Purpose of the Study:

  • To assess changes in growth, body composition, and growth-related biochemical markers after A&T in prepubertal children.
  • To compare growth parameters in children with ATH to healthy controls.

Main Methods:

  • A prospective study followed 28 children (3-10 years) with ATH for 1 year post-A&T.
  • Growth parameters (height, weight) and biomarkers (IGF-1, IGFBP-3) were measured preoperatively and at 6 months and 1 year post-surgery.
  • A control group of 20 healthy children was also monitored.

Main Results:

  • Children with ATH showed significant increases in height and weight post-A&T.
  • Height velocity accelerated, particularly in the second 6 months after surgery.
  • Preoperative low IGF-1 levels normalized post-A&T, with significant increases in IGFBP-3.

Conclusions:

  • Children with ATH experience slower growth rates, not necessarily significant retardation.
  • A&T promotes weight gain and elevates IGF-1, leading to accelerated linear growth.
  • These changes suggest an increase in growth hormone (GH) levels or effect following A&T.
Abstract

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