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The effect of packaging materials on the stability of sunscreen emulsions
Maria Inês R M Santoro1, Daniella Almança Gonçalves Da Costa E Oliveira, Erika R M Kedor-Hackmann
1Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, Caixa Postal 66083, CEP 05315-970 São Paulo, SP, Brazil. ines@usp.br
Abstract:
The purpose of this research was to study the stability of a emulsion containing UVA, UVB and infrared sunscreens after storage in different types of packaging materials (glass and plastic flasks; plastic and metallic tubes). The samples, emulsions containing benzophenone-3 (B-3), octyl methoxycinnamate (OM) and Phycocorail, were stored at 10, 25, 35 and 45 degrees C and representative samples were analyzed after 2, 7, 30, 60 and 90 days period. The stability studies were conducted by analyzing samples at pre-determined intervals by high performance liquid chromatography (HPLC) along with periodic rheological measurements.
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