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Updated: Aug 18, 2026

Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
Published on: April 1, 2015
Focal nodular hyperplasia after busulfan treatment
F G Foschi1, P Savini, G Marano
1Department of Internal Medicine, Faenza Hospital, Via Stradone no. 9, 48018 Faenza (RA), Italy. fgfoschi@tin.it
Abstract:
The case of a 48-year-old woman in whom focal nodular hyperplasia of the liver developed after busulfan therapy was administered for essential thrombocytosis is described. Focal nodular hyperplasia is a reactive disorder related to a circulation disorder. The close temporal relation between the haematological disease, busulfan treatment and the appearance of hyperplastic diseases of the liver in our patient supports the possibility that the association of the events might not be casual.
