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Updated: Jul 15, 2026

Proofreading and DNA Repair Assay Using Single Nucleotide Extension and MALDI-TOF Mass Spectrometry Analysis
Published on: June 19, 2018
DNA mismatch detection using a pyrene-excimer-forming probe
Kazushige Yamana1, Yudai Fukunaga, Yusuke Ohtani
1Department of Materials Science and Chemistry, University of Hyogo, 2167 Shosha, Himeji, Hyogo 671-2201, Japan. yamana@eng.u-hyogo.ac.jp
Abstract:
A pyrene-excimer-forming probe allowed the easy and sensitive detection of a single base mismatch in target DNA. This was due to the faster strand exchange rate compared to a fully-matched target.
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