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Related Experiment Videos

Hyperhidrosis: evolving therapies for a well-established phenomenon.

John H Eisenach1, John L D Atkinson, Robert D Fealey

  • 1Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA. eisenach.john@mayo.edu

Mayo Clinic Proceedings
|May 13, 2005
PubMed
Summary
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Excessive sweating, or hyperhidrosis, involves non-thermoregulatory sweating often linked to emotional stimuli. Treatment varies by severity, ranging from antiperspirants to surgical options like endoscopic thoracic sympathectomy.

Area of Science:

  • Neurology
  • Dermatology
  • Medical Science

Background:

  • Hyperhidrosis, characterized by excessive sweating, is a socially embarrassing disorder with various subtypes including palmar-plantar, palmar-axillary, isolated axillary, and craniofacial.
  • A key feature is excessive, non-thermoregulatory sweating, often triggered by emotional stimuli, affecting areas influenced by the anterior cingulate cortex.

Purpose of the Study:

  • To review the distinct types of hyperhidrosis and their underlying mechanisms.
  • To outline the diagnostic approaches for hyperhidrosis.
  • To discuss the spectrum of treatment options available for different hyperhidrosis subtypes.

Main Methods:

  • Diagnosis relies on patient history, physical examination, and laboratory studies using indicator powder to assess sweat distribution and thermoregulatory function.

Related Experiment Videos

  • Treatment strategies are presented on a continuum, from conservative measures to more invasive procedures.

    • Main Results:

    • Treatment options include antiperspirants, anticholinergics, iontophoresis, botulinum toxin type A, local excision/curettage, and endoscopic thoracic sympathectomy.
    • The choice of treatment depends on the hyperhidrosis subtype, severity, and patient-specific risk-benefit analysis.

    Conclusions:

    • Effective management of hyperhidrosis requires a tailored approach based on individual patient needs and condition severity.
    • Further discussion addresses the long-term outcomes associated with hyperhidrosis and its various treatments.