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Published on: October 16, 2010
[Breast cancer associated with pregnancy]
José Francisco Gallegos-Hernández1
1Hospital de Oncología, Centro Médico Nacional Siglo XXI. gal@govame.com
Abstract:
Invasive breast carcinoma diagnosed during pregnancy and even one year after delivery is known as breast cancer associated with pregnancy. There are many controversies surrounding this entity concerning diagnosis and therapeutics as well as to the behavior regarding the fetus. There is broad information in the existing literature. We can find authors who do not change the diagnostic-therapeutic approach to the neoplasia and those who even advise pregnancy interruption and consider greater aggressiveness in treatment, in comparison to the same cancer in a non-pregnant woman. The prognosis of breast cancer associated with pregnancy has also been a controversial issue. Historically, it has been considered to have the worst evolution. Nevertheless, evidence recently has shown that the known prognosis factors in breast cancer (stage, nodular status, receptors, etc.) are those associated with the prognosis and not the pregnancy itself. The objective of this article is to analyze, based on the existing evidence in the literature, which is the best diagnostic-therapeutic route for breast cancer associated with pregnancy, which procedures must be followed with the mother and the fetus and which is the ideal therapeutic sequence, analyzing at the same time the possibilities of axillary preservation by means of lymphatic mapping and sentinel node biopsy in these patients.
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