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Updated: Aug 18, 2026

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
Published on: October 1, 2019
Brain natriuretic peptide in patients with congestive heart failure and central sleep apnea
Carmen Carmona-Bernal1, Esther Quintana-Gallego, Manuel Villa-Gil
1Medical-Surgical Unit of Respiratory Diseases, Virgen del Rocío University Hospital, Seville, Spain. ccarmona@cica.es <ccarmona@cica.es>
Study Objective:
To assess the possible relationship between Cheyne-Stokes respiration (CSR) associated with central sleep apnea (CSA) syndrome and brain natriuretic peptide (BNP) in an outpatient population presenting with stable congestive heart failure (CHF).
Measurements And Results:
Ninety patients with CHF due to systolic dysfunction (left ventricular ejection fraction
Conclusion:
Patients with CHF and CSR-CSA have higher BNP levels than those without CSR-CSA. Our results suggest that CSR-CSA and BNP levels are related. However, the possibility that both factors might be independent expressions of the functional status of CHF patients cannot be ruled out.
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