Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human pythiosis, Brazil.

Sandra de Moraes Gimenes Bosco1, Eduardo Bagagli, João Pessoa Araújo

  • 1Department of Pathology, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.

Emerging Infectious Diseases
|May 14, 2005
PubMed
Summary

Pythiosis, a rare infection caused by Pythium insidiosum, is challenging to diagnose. This study reports the first human case in Brazil, confirmed through culture and rDNA sequencing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First case of canine paraprostatic infection caused by a high-risk ST147 Klebsiella pneumoniae harboring multiple extended-spectrum-β-lactamase genes.

Veterinary research communications·2026
Same author

Molecular epidemiological surveillance of circovirus in avian and mammalian species on the Brazilian coast.

Archives of virology·2026
Same author

Ki-67 staining pattern as a prognostic biomarker for advanced acral melanoma.

Anais brasileiros de dermatologia·2026
Same author

Retinoid X Receptor Alpha and Melanocytes: A Translational Perspective.

Pathology international·2026
Same author

Microbial Diversity and Composition Uncovered on Obturator Prosthesis Biofilms: Exploratory Findings from a Pilot Study.

Pathogens (Basel, Switzerland)·2026
Same author

In vitro performance of eugenol and cinnamaldehyde on biofilms produced by <i>Candidozyma auris</i>.

Biofouling·2026

Area of Science:

  • Infectious Diseases
  • Mycology
  • Emerging Pathogens

Background:

  • Pythiosis is a life-threatening infection caused by the oomycete Pythium insidiosum.
  • The pathogen is commonly found in aquatic environments.
  • Human infections are rare and often misdiagnosed due to non-specific clinical and histopathological features.

Observation:

  • This paper details the first documented human case of pythiosis in Brazil.
  • The patient acquired the infection from an aquatic source.
  • Initial diagnostic attempts were complicated by the non-pathognomonic nature of the disease.

Findings:

  • Definitive diagnosis was achieved using a combination of fungal culture and ribosomal DNA (rDNA) sequencing.
  • Molecular methods, specifically rDNA sequencing, proved crucial for accurate identification of Pythium insidiosum.

Related Experiment Videos

  • Culture provided a viable method for pathogen isolation and subsequent analysis.

    • Implications:

    • This case highlights the importance of considering pythiosis in the differential diagnosis of severe infections, especially in endemic regions.
    • Accurate and timely diagnosis, aided by molecular techniques, is critical for effective patient management.
    • Increased awareness and diagnostic capabilities are needed to address this emerging public health concern.