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Updated: Aug 18, 2026

Dissection and Coronal Slice Preparation of Developing Mouse Pituitary Gland
Published on: November 16, 2017
The ancestry of the prolactin-releasing hormone precursor
M C Lagerström1, R Fredriksson, T K Bjarnadottir
1Department of Neuroscience, Uppsala University, Biomedical Center, Sweden.
Abstract:
The prolactin-releasing hormone (PRLH) is implicated in food intake and is expressed in several parts of the mammalian brain. The origin of the peptide precursor (PRH) has been unclear, and the only feature resembling other known human neuropeptide sequences is the C-terminal RF-motif, also present in the neuropeptide FF and the neuropeptide RF amide-related peptide families (RFRP). We have recently found sequences of PRH and the closely related precursor C-RF amide in chicken, shedding light on the PRH ancestry.
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