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Smoking and psoriasis.

Shahrad M Behnam1, Shahdad E Behnam, John Y Koo

  • 1Oregon Health Sciences and University School of Medicine, Portland, OR, USA.

Skinmed
|May 14, 2005
PubMed
Summary
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Smoking significantly increases psoriasis risk, especially in women. For male psoriasis patients, heavy smoking may worsen extremity symptoms and reduce treatment effectiveness, highlighting the need to discourage smoking.

Area of Science:

  • Dermatology
  • Epidemiology

Background:

  • Early studies suggested a link between tobacco use and psoriasis.
  • These studies often failed to control for alcohol consumption, leading to inconsistent results.

Purpose of the Study:

  • To review literature on smoking and psoriasis, controlling for confounders like alcohol.
  • To clarify the relationship between smoking and psoriasis development and severity.

Main Methods:

  • Literature review of studies assessing smoking and psoriasis.
  • Focus on studies that controlled for alcohol consumption.

Main Results:

  • Alcohol-controlled studies indicate women smokers have a 3.3-fold increased risk of plaque psoriasis.
  • Heavy smoking in male psoriasis patients may correlate with more severe extremity disease.

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  • Smoking reduces treatment improvement rates for both male and female psoriasis patients.

    • Conclusions:

    • Smoking is an important risk factor for psoriasis, particularly in women.
    • Discouraging smoking is crucial for managing psoriasis and improving treatment outcomes.