Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dual-phase multidetector thin-section CT in detecting duodenal gastrinoma.

A C Pfannenberg1, C Burkart, S M Kröber

  • 1Department of Diagnostic Radiology, University of Tuebingen, Hoppe-Seyler-Str. 3, 72076 Tuebingen, Germany. christina.pfannenberg@med.uni-tuebingen.de

Abdominal Imaging
|May 14, 2005
PubMed
Summary

Preoperative localization of gastrinomas, particularly those outside the pancreas, is difficult. This case highlights dual-phase computed tomography as a key imaging technique for detecting duodenal gastrinomas, aiding surgical planning.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "mFOLFOX6 versus mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214) and the ABCSG (R-06)": [ESMO Open 9 (2024) 103703].

ESMO open·2025
Same author

mFOLFOX6 versus mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214).

ESMO open·2024
Same author

[Rosai-Dorfman disease as a rare cause of a pancreatic mass].

Der Pathologe·2020
Same author

Improving therapeutic efficacy of IL-12 intratumoral gene electrotransfer through novel plasmid design and modified parameters.

Gene therapy·2018
Same author

Coronary and carotid atherosclerosis in asymptomatic male marathon runners.

Scandinavian journal of medicine & science in sports·2017
Same author

Preoperative breast MR Imaging in patients with primary breast cancer has the potential to decrease the rate of repeated surgeries.

European journal of radiology·2017

Area of Science:

  • Gastroenterology
  • Radiology
  • Oncology

Background:

  • Preoperative localization of gastrinomas, especially extrapancreatic ones, poses a significant challenge for radiologists.
  • Many patients with extrapancreatic gastrinomas proceed to surgery without preoperative identification of the primary tumor, complicating management.
  • The optimal imaging modality for gastrinoma localization is a subject of ongoing discussion.

Observation:

  • A case of a duodenal gastrinoma with regional lymph node metastases presenting as Zollinger-Ellison syndrome is reported.
  • The small primary tumor was successfully detected noninvasively using dual-phase multidetector thin-section computed tomography.
  • Adequate bowel distention was crucial for successful imaging during the computed tomography scan.

Findings:

Related Experiment Videos

  • Dual-phase multidetector thin-section computed tomography with adequate bowel distention enabled noninvasive detection of a small duodenal gastrinoma.
  • Endoscopy and histopathologic examination confirmed the diagnosis of the primary tumor.
  • The findings underscore the importance of specific computed tomography techniques and protocols for extrapancreatic gastrinoma localization.

Implications:

  • This case demonstrates the efficacy of a meticulous computed tomography approach in localizing challenging extrapancreatic gastrinomas.
  • Accurate preoperative localization can significantly improve surgical planning and patient outcomes for Zollinger-Ellison syndrome.
  • Further research into optimal imaging protocols for rare gastrinoma presentations is warranted.