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Chronic pain in persons with multiple sclerosis
Dawn M Ehde1, Travis L Osborne, Mark P Jensen
1Department of Rehabilitation Medicine, Box 356490, University of Washington School of Medicine, Seattle, WA 98195-6490, USA. ehde@u.washington.edu
Abstract:
The MS literature clearly indicates that chronic pain is a significant problem for many, although not all, persons with MS. The rates of pain have been found to vary in different studies, from 44% to 80%, depending on the sample and the specific questions used to assess the incidence and severity of pain. What is not clear is the proportion of persons who have acute pain relative to chronic pain. Although the specific frequency of pain problems in patients with MS may not be clear, there is a subgroup of patients (about 38% of those with pain in one sample) who report experiencing severe pain [8]. Preliminary research suggests that chronic pain can have a significant negative impact on a number of aspects of functioning in persons with MS, such as the ability to engage in household work and psychologic functioning. A biopsychosocial model of chronic pain, which has proved to be useful in understanding chronic pain as a primary condition and chronic pain in persons with other physical disabilities, may also be useful for understanding pain in persons with MS. Research,however, has not yet tested the utility of this model among MS populations. Longitudinal research is needed to help us learn how MS-related pain may fluctuate over time and with changes in disease status. There also is a strong need for research that examines access to pain treatment and that evaluates the efficacy of currently available pain treatments in persons with MS. The results of such research, as it is applied to help patients with MS, should contribute to an overall increase in well-being and a decrease in suffering among persons with MS and chronic pain.
Insights
Chronic pain affects many individuals with Multiple Sclerosis (MS), impacting daily life and functioning. Further research is crucial to understand pain fluctuations, treatment access, and efficacy for improved well-being.
Area of Science:
- Neurology
- Pain Medicine
- Rehabilitation
Background:
- Chronic pain is prevalent in Multiple Sclerosis (MS), affecting 44-80% of individuals.
- A significant subgroup experiences severe pain, impacting daily functioning and psychological well-being.
- The exact incidence of acute versus chronic pain in MS remains unclear.
Purpose of the Study:
- To review the current understanding of chronic pain in MS.
- To highlight the need for research on pain management and treatment efficacy in MS patients.
- To explore the potential utility of a biopsychosocial model for MS-related pain.
Main Methods:
- Literature review of existing studies on pain in MS.
- Analysis of pain prevalence, severity, and impact on functioning.
- Discussion of research gaps and future directions.
Main Results:
- Chronic pain is a significant issue in MS, with varying reported rates.
- Severe pain is experienced by a notable percentage of those with MS pain.
- Preliminary evidence suggests negative impacts on functional abilities and psychological health.
Conclusions:
- A biopsychosocial model may be applicable to MS-related pain, but requires empirical testing.
- Longitudinal research is needed to track pain fluctuations with disease progression.
- Enhanced understanding of treatment access and efficacy is critical for improving patient outcomes and reducing suffering.
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