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[Zinc and pregnancy].

M Favier1, I Hininger-Favier

  • 1Service d'obstétrique, gynécologie et médecine de la reproduction, hôpital Sud, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France. MFavier@chu-grenoble.fr

Gynecologie, Obstetrique & Fertilite
|May 17, 2005
PubMed
Summary

Prenatal zinc deficiency may negatively impact pregnancy outcomes. Supplementation shows promise for infant neurobehavioral development and is considered safe during pregnancy.

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Area of Science:

  • Biochemistry
  • Developmental Biology
  • Nutritional Science

Context:

  • Zinc is an essential trace element vital for cellular integrity, protein synthesis, and nucleic acid metabolism.
  • These functions are crucial for cell division and growth, highlighting zinc's importance in fetal development.
  • Increased zinc requirements during pregnancy are recognized, yet accurate deficiency assessment remains challenging.

Purpose:

  • To review the potential adverse effects of gestational zinc deficiency on pregnancy outcomes.
  • To evaluate the current evidence regarding prenatal zinc supplementation and its impact on maternal and infant health.

Summary:

  • Gestational zinc deficiency may compromise pregnancy outcomes.
  • Preliminary human studies indicate that prenatal zinc supplementation can positively influence infant neurobehavioral development.
  • Zinc supplementation at 30 mg/day, a therapeutic dose for other conditions, is deemed safe during pregnancy.

Impact:

  • Highlights the critical role of zinc in ensuring healthy fetal development and pregnancy outcomes.
  • Suggests prenatal zinc supplementation as a potential strategy to mitigate risks associated with zinc deficiency.
  • Provides evidence for the safety of therapeutic zinc loads during pregnancy, supporting further research and clinical application.

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