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Assessment of Ex Vivo Murine Biventricular Function in a Langendorff Model
Published on: December 23, 2022
Preserved systolic function with isolated left ventricular noncompaction in an elderly patient
Dursun Aras1, Omac Tufekcioglu, Serkan Topaloglu
1Turkiye Yuksek Ihtisas Hospital, Department of Cardiology, Ankara, Turkey. sevgidursun06@yahoo.com
Insights
Isolated left ventricular noncompaction (IVNC) is a rare heart condition. This report details the oldest known case of IVNC in an elderly patient with preserved heart function.
Area of Science:
- Cardiology
- Genetics
- Embryology
Background:
- Isolated left ventricular noncompaction (IVNC) is a rare congenital cardiomyopathy.
- It arises from abnormal endomyocardial embryogenesis.
- Clinical features include heart dysfunction, embolism, and arrhythmias.
Observation:
- A 78-year-old patient was diagnosed with IVNC.
- The patient presented with preserved left ventricular systolic function.
- This is the oldest reported case of IVNC with preserved LV function.
Findings:
- IVNC can occur in elderly individuals.
- Preserved left ventricular systolic function is possible in older IVNC patients.
- The clinical characterization and natural course of IVNC in the elderly require further study.
Implications:
- This case expands the known age range for IVNC diagnosis.
- It highlights the importance of considering IVNC in elderly patients with heart conditions.
- Further research is needed to understand IVNC's long-term effects in older populations.
Abstract:
Isolated left ventricular noncompaction (IVNC) is a rare congenital cardiomyopathy resulting from an arrest in normal endomyocardial embryogenesis. Clinical presentations of IVNC include systolic and diastolic dysfunction, systemic embolism and ventricular arrhythmias. In recent years there has been an increasing awareness of this anomaly; however, especially in elderly, clinical characterization and natural course of IVNC are still in question. In this case, we report a case of a 78-year-old patient with the diagnosis of IVNC with preserved left ventricular (LV) systolic function. To the best of our knowledge, this is the oldest IVNC case with preserved LV systolic function in the literature.
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