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Published on: October 16, 2021
Complications of supra-annular mitral valve placement in infants
C L Barker1, P E F Daubeney, E A Shinebourne
1Royal Brompton Hospital, London, UK. cbarker@doctors.org.uk
Insights
Supra-annular prosthetic mitral valve placement in infants aimed to delay replacement but led to cardiac dysfunction. The strategy failed to prevent subsequent valve replacement due to adverse atrial and pressure changes.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Biomedical Engineering
Background:
- Supra-annular prosthetic mitral valve placement is a surgical technique used in infants.
- The goal of this technique is to implant a larger valve to postpone the need for reoperation.
Observation:
- Two infants received supra-annular prosthetic mitral valves.
- The procedure was initially successful in both cases.
Findings:
- Cardiac function impairment developed in both patients by two and three years post-surgery.
- The prosthetic valve reduced left atrial volume and compliance, leading to elevated left atrial and pulmonary venous pressures.
- The atrium below the prosthesis (ventricularised atrium) dilated.
Implications:
- This supra-annular approach may not effectively delay the need for repeat mitral valve replacement in infants.
- Adverse hemodynamic changes in the left atrium and pulmonary vasculature can occur.
- Further research is needed to evaluate long-term outcomes and alternative strategies for pediatric mitral valve replacement.
Abstract:
Two infants underwent supra-annular placement of prosthetic mitral valves. The objective of this strategy was to insert a larger valve and delay replacement. This approach was initially successful but by two and three years later the patients developed impairment of cardiac function. The prosthesis decreased the volume and compliance of the left atrium causing high left atrial and pulmonary venous pressures. The "ventricularised" atrium below the prosthesis dilated. In neither case was it possible to delay second valve replacement.
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