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Successfully treated mitral valve Proteus mirabilis endocarditis

Michael Lloyd1, Lewis Satterwhite, Stamatios Lerakis

  • 1Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.

The American Journal of the Medical Sciences
|May 17, 2005
PubMed

Insights

Infective endocarditis caused by Proteus mirabilis is rare and often fatal. This case highlights successful treatment with antibiotics and surgery for P. mirabilis endocarditis.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Proteus mirabilis is a Gram-negative bacterium rarely associated with infective endocarditis.
  • Infective endocarditis caused by P. mirabilis has a high mortality rate.

Observation:

  • A 64-year-old male presented with symptoms including fever, dysuria, and a heart murmur.
  • Diagnosis of P. mirabilis endocarditis was confirmed by clinical signs, positive blood cultures, and echocardiographic evidence of a large mitral valve vegetation.

Findings:

  • The patient received prolonged antibiotic therapy and underwent successful surgical mitral valve replacement.
  • Review of literature indicates P. mirabilis endocarditis is uncommon and carries a grave prognosis.

Implications:

  • This case demonstrates that aggressive management, including antibiotics and valve surgery, can lead to favorable outcomes in P. mirabilis endocarditis.
  • Further research into the clinical characteristics and optimal treatment strategies for this rare condition is warranted.

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