Related Experiment Video

Updated: Aug 18, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
05:25

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft

Published on: September 15, 2023

Effect of coronary artery bypass grafting and aneurysmectomy on QT dispersion in moderate or severe left ventricular

Oner Gulcan1, Alpay T Sezgin, Senol Demircan

  • 1Department of Cardiovascular Surgery, Adana Teaching and Medical Research Center, Baskent University, Adana, Turkey. drgulcan@yahoo.com

American Heart Journal
|May 17, 2005
PubMed

Insights

Combined coronary artery bypass grafting (CABG) and aneurysmectomy significantly decreased QT dispersion (QTd) in patients with left ventricular dysfunction, according to Fridericia (QT CF) and Sagie et al (QT CS) methods. This finding suggests improved cardiac electrical stability post-surgery.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Electrophysiology

Background:

  • Patients with moderate to severe left ventricular dysfunction often require complex cardiac procedures.
  • Assessing the impact of combined surgical interventions on cardiac electrical stability is crucial for patient outcomes.

Purpose of the Study:

  • To evaluate the effect of simultaneous coronary artery bypass grafting (CABG) and aneurysmectomy on QT dispersion (QTd).
  • To analyze changes in QTd in patients with compromised left ventricular function undergoing combined cardiac surgery.

Main Methods:

  • QT interval and QT dispersion (QTd) were measured in 44 patients before and 1 month after combined CABG and aneurysmectomy.
  • Heart rate correction was performed using Bazett (QT CB), Fridericia (QT CF), and Sagie et al (QT CS) formulas.

Main Results:

  • QTd significantly decreased post-surgery when analyzed using Fridericia (QT CF) and Sagie et al (QT CS) methods (P < .05).
  • The Bazett (QT CB) method showed a significant increase in QTd post-surgery (P < .05).
  • Postoperative QTd values were consistently lower across validated correction methods, indicating improved electrical stability.

Conclusions:

  • Combined CABG and aneurysmectomy lead to a significant reduction in QT intervals and QT dispersion.
  • The findings, particularly using Fridericia (QT CF) and Sagie et al (QT CS) correction methods, suggest improved cardiac electrical stability after the combined procedure.
Abstract

More Related Videos

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery09:12

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Published on: March 27, 2018

Related Concept Videos

Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...